A new study published in January 2014 entitled " On the relationship between the vaccine against human papilloma virus and autoimmune diseases , "is destined to reopen the controversy surrounding the numerous reports of damage induced by the HPV vaccine , which have surfaced since its widespread use, starting with the FDA approval in 2006 of the vaccine Gardasil , Merck & Co. With the billion dollar campaign waged by the Brazilian government, where more than 5 million pre-teens be vaccinated, can expect a flood of new cases of immune diseases
's study points out that " with the introduction of HPV vaccines , several cases of onset or exacerbation of autoimmune diseases after application of the vaccine have been reported in bibliographic databases and pharmacovigilance, causing concerns about their safety . "
A new study published in January 2014 entitled " On the relationship between the vaccine against human papilloma virus and autoimmune diseases , "is destined to reopen the controversy surrounding the numerous reports of damage induced by the HPV vaccine , which have surfaced since its widespread use, starting with the FDA approval in 2006 of the vaccine Gardasil , Merck & Co. With the billion dollar campaign waged by the Brazilian government, where more than 5 million pre-teens be vaccinated, can expect a flood of new cases of immune diseases.
's study points out that " with the introduction of HPV vaccines , several cases of onset or exacerbation of autoimmune diseases after application of the vaccine have been reported in bibliographic databases and pharmacovigilance, causing concerns about their safety . "
After an extensive review of the biomedical literature, they listed the conditions under which the HPV vaccination is probably linked to the development of autoimmune diseases, including:
Part of the explanation lies in a phenomenon known as " molecular mimicry "defined as the ability of the immune system confuse a structure with a foreign peptide (generally pathogens) and thereby cause autoimmune damage. antibodies, for example, which are produced against a specific pathogen can react crossreact with proteins in the body that have a similar or identical sequence
Acute disseminated encephalomyelitis and other demyelinating diseases of the central nervous system
Multiple Sclerosis (MS)
Guillain - Barré syndrome (GBS)
Primary ovarian failure (POF)
Bullosus IgA dermatitis
Henoch-Schonlein purpura
Cutaneous vasculitis
Of Kikuch-Fujimoto disease
Erythema multiforme
Acute cerebral ataxia
Immune Thrombocytopenic Purpura
The authors caution that:
" The decision to vaccinate against HPV is a personal decision, not one that should be made to the public health. HPV is not a lethal disease in 95% of infections, and the other 5% are detectable and treatable phase pre-cancerous. "
HPV Vaccines can cause the immune system to attack the body
How could a vaccine that has been declared safe and effective worldwide to be connected to a wide range of autoimmune diseases?
Exactly the same possibility is addressed in a pioneering article entitled " Quantifying the possible risk of cross-reactivity of HPV16 vaccine , "published in 2009 in the Journal of Experimental Therapeutics and Oncology . The article describes the background to the issue as follows:
"The potential for adverse events associated with vaccination for infectious diseases highlight the need for effective analysis and definition of possible vaccine side effects. Using the HPV16 proteome as a model, we quantified the actual and theoretical risks of anti-HPV16 vaccination, and define The potential range of diseases derived from concomitant cross-reactivity with the human body. "
HPV16 proteomics is the full spectrum of proteins produced by HPV16 virus, which are present in both HPV vaccines ( Gardasil and Cervarix). Each protein has a risk of inducing an immune response that could, in theory, give a side effect in self structures within the human proteome. With this possibility in mind, the researchers used the following method to determine the probability of an event occurring as this:
"We looked into the primary sequence of the HPV16 proteome heptamers amino acid sequences shared with human proteins using the database Resources International Protein."
Heptamers amino acid sequences are defined as oligomers (molecular complex) with seven subunits
Results of his research revealed a profound degree of correspondence:
"The human proteome contains 82 heptapeptides and octapeptides found in HPV16 two. Viral correspondences are scattered among the proteins involved in key processes such as differentiation and cell growth regulation and sensorineural. Human proteins heptamers containing the HPV16-derived molecules include cell adhesion of leukocyte differentiation antigens, enzymes, proteins associated with spermatogenesis, transcription factors and neuronal antigens. viral The number of matches and their locations become almost inevitable occurrence of side cross autoimmune reactions in the human host after HPV16-based vaccination . "
The so-called "inevitability" of "side autoimmune cross-reactions in the human host after vaccination HPV16-based" is a major concern , especially considering that there are 4 in total strains in the vaccine Gardasil and Cervarix in 2, significantly increasing the range of Proteomic overlap between viral and human proteins and the subsequent molecular mimicry . Furthermore, it is important to recognize that never proved that the vaccine prevented a single death of cervical cancer, and yet millions are being exposed to their probable "unavoidable risks" to health
Read more: http://www.anovaordemmundial.com/2014/03/estudo-revela-perigos-inevitaveis-doencas-auto-imunes-das-vacinas-contra-HPV.html#ixzz2vtLAzXLz
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